Cell Type Annotation Made Simple

Automated scRNA-seq annotation using state-of-the-art AI models

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What is Cell Type Annotation?

Cell type annotation is the process of identifying and labeling different cell types in single-cell RNA sequencing (scRNA-seq) data. This crucial step in single-cell analysis helps researchers understand cellular diversity, disease mechanisms, and developmental processes.

Traditional Methods

Manual annotation relies on marker genes and expert knowledge, which is:

  • Time-consuming (hours to days)
  • Subjective and inconsistent
  • Limited by human expertise

AI-Powered Annotation

Our automated approach uses multiple LLMs for:

  • Fast annotation (minutes)
  • Consistent results
  • Consensus-based accuracy
  • Continuous learning

Why mLLMCelltype?

We combine multiple AI models for superior results:

  • GPT-4, Claude 3, Gemini integration
  • Cross-validation between models
  • Higher accuracy than single-model tools
  • Free web-based platform

How Our Cell Type Annotation Works

Simple 3-step process for accurate scRNA-seq annotation

1

Upload Data

Upload your scRNA-seq expression matrix in CSV, TSV, or Excel format

2

AI Analysis

Multiple LLMs analyze your data and reach consensus on cell types

3

Get Results

Download annotated results with confidence scores and detailed reports

Cell Type Annotation Features

🧬 Supported Data Types

  • Single-cell RNA-seq (scRNA-seq)
  • Marker gene lists
  • Expression matrices
  • Multiple species support

🤖 AI Models

  • GPT-4 and GPT-4 Turbo
  • Claude 3 Opus & Sonnet
  • Google Gemini Pro
  • 8+ model providers

📊 Output Formats

  • Annotated cell type labels
  • Confidence scores
  • Model consensus metrics
  • Exportable reports

Cell Type Annotation FAQ

What file formats are supported for cell type annotation?
We support CSV, TSV, and Excel files containing marker genes or expression matrices from your scRNA-seq experiments.
How accurate is automated cell type annotation?
Our multi-model consensus approach achieves 85-95% accuracy compared to expert manual annotation, with the added benefit of consistency and speed.
Can I use this for any species?
Yes! Our cell type annotation supports human, mouse, rat, zebrafish, and many other species. You can specify your species during the annotation process.
Is my scRNA-seq data secure?
Absolutely. All data is processed securely and automatically deleted after your session. We don't store any research data permanently.

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Why Automated Cell Type Annotation Matters

In the era of single-cell genomics, accurate cell type annotation is fundamental to understanding biological systems. Traditional manual annotation methods are becoming impractical as datasets grow larger and more complex. Our AI-powered cell type annotation tool addresses these challenges by providing:

Applications of Cell Type Annotation

Our automated annotation platform is used in various research areas: